194

Church GM, Gao Y, Kosuri S (2012) Next-generation digital information storage in DNA. Science

337(6102):1628. (Epub 2012 Aug 16. PubMed PMID: 22903519 * First work to show the great

potential of DNA as storage: exabytes per gram of DNA are possible to store)

Dandekar T (2013) Molekulare hoch integrierte Datenspeicherung über aktiv gesteuerte DNA. DPA

102013 004584.3 (Offenlegungsschrift DPA DE 102014 005549 A1 2014.10.23 C12Q 1/02 *

This work explains in more detail how light-guided polymerases and exonucleases can be used

to read in or out DNA.)

Dandekar T (2015) Intelligente Nanozellulosefolie für verbesserte Chipkarten. DPA vom 27.04.2015

Aktenzeichen DE 102015 005307.8

Dandekar T (2016) Modified bacterial nanocellulose and its uses in chip cards and medicine PCT

U30719WO (published 3rd Nov 2016 * All details and our current experiments on the nanocel­

lulose chip are described here for replication. However, there is still some development work to

be done [a “proof of concept” is there, but a real prototype still needs time])

Dandekar T, Lopez D (2015) Programmable bacterial membranes with active DNA storage. Emerging

Technology Finalist presentation, Royal Society for Chemistry, University of Würzburg, London

(29.6.2015)

Dandekar T, Lopez D, Schaack D (2013) Active DNA storage is essential. Nature 494:80. (Comment

[posted 17.4.13] reviewed and recommended by the Nature Editor on: Goldman N, Bertone P,

Chen S, Dessimoz C, LeProust EM, Sipos B, Birney E. Towards high-capacity, low-maintenance

information storage in synthesized DNA. Nature 494:77–80)

Drexler KE (1986) Engines of creation: the coming era of nanotechnology. Doubleday (0-385-19973-2

* This work draws attention well to the high potential, but also to potential dangers of nanotech­

nology. In particular, the design of a nanomachine should exclude self-sufficiency or autonomy

from the outset [no “grey goose syndrome”])

Ganesan P, Ranganathan R, Chi Y et al (2016) Functional pyrimidine-based thermally activated

delay fluorescence emitters: photophysics, mechanochromism and fabrication of organic light-­

emitting diodes. Chemistry 28. https://doi.org/10.1002/chem.201604883. ([Epub ahead of print]

PubMed PMID: 28028848)

Goldman N, Bertone P, Chen S et  al (2013) Towards practical, high-capacity, low-maintenance

information storage in synthesized DNA.  Nature 494(7435):77–80. https://doi.org/10.1038/

nature11875. (Epub 2013 Jan 23. PubMed PMID: 23354052; PubMed Central PMCID:

PMC3672958 * Second work on DNA storage. Demonstrates convincingly that text, images, and

sounds can be stored well in DNA and read out again with modern NGS technology a little time

consuming. Sequencing twice removes random errors for clear image decoding, for example.

But: everything still quite slow, no concept for a computer chip yet)

Grass RN, Heckel R, Puddu M (2015) Robust chemical preservation of digital information on DNA

in silica with error-correcting codes. Angew Chem Int Ed Engl 54(8):2552–2555. https://doi.

org/10.1002/anie.201411378. (Epub 2015 Feb 4. PubMed PMID: 25650567 * Third work on

DNA storage. Here, the chemists around Prof. Stark show how long information can be stored

in DNA if chemistry and error correction codes support [literally millions of years – as we also

see through our evolution])

Hekstra DR, White KI, Socolich MA (2016) Electric-field-stimulated protein mechanics. Nature

540(7633):400–405. https://doi.org/10.1038/nature20571. (* Current work on “electronic”

proteins.)

Hoffmann J, Trotter M, von Stetten F et al (2012) Solid-phase PCR in a picowell array for immobi­

lizing and arraying 100,000 PCR products to a microscope slide. Lab Chip 12(17):3049–3054.

https://doi.org/10.1039/c2lc40534b. (Epub 2012 Jul 23. PubMed PMID: 22820686 *Here, high

storage density of DNA is achieved by modern chip methods.)

13  Life Invents Ever New Levels of Language